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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1911 1
1912 1
1915 1
1917 1
1922 3
1923 1
1929 1
1936 1
1945 1
1946 3
1947 4
1948 2
1950 5
1951 7
1952 11
1953 10
1954 14
1955 11
1956 11
1957 15
1958 22
1959 15
1960 15
1961 17
1962 26
1963 50
1964 51
1965 27
1966 9
1967 9
1968 10
1969 14
1970 12
1971 25
1972 16
1973 27
1974 33
1975 32
1976 29
1977 53
1978 41
1979 39
1980 43
1981 41
1982 34
1983 39
1984 45
1985 37
1986 25
1987 23
1988 28
1989 24
1990 46
1991 42
1992 42
1993 43
1994 27
1995 40
1996 26
1997 34
1998 32
1999 25
2000 19
2001 43
2002 22
2003 27
2004 28
2005 25
2006 23
2007 19
2008 24
2009 20
2010 26
2011 24
2012 23
2013 19
2014 34
2015 23
2016 27
2017 25
2018 25
2019 28
2020 34
2021 43
2022 33
2023 30
2024 14

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1,956 results

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Page 1
Tay-Sachs disease.
Fernandes Filho JA, Shapiro BE. Fernandes Filho JA, et al. Arch Neurol. 2004 Sep;61(9):1466-8. doi: 10.1001/archneur.61.9.1466. Arch Neurol. 2004. PMID: 15364698 Review. No abstract available.
AAV gene therapy for Tay-Sachs disease.
Flotte TR, Cataltepe O, Puri A, Batista AR, Moser R, McKenna-Yasek D, Douthwright C, Gernoux G, Blackwood M, Mueller C, Tai PWL, Jiang X, Bateman S, Spanakis SG, Parzych J, Keeler AM, Abayazeed A, Rohatgi S, Gibson L, Finberg R, Barton BA, Vardar Z, Shazeeb MS, Gounis M, Tifft CJ, Eichler FS, Brown RH Jr, Martin DR, Gray-Edwards HL, Sena-Esteves M. Flotte TR, et al. Nat Med. 2022 Feb;28(2):251-259. doi: 10.1038/s41591-021-01664-4. Epub 2022 Feb 10. Nat Med. 2022. PMID: 35145305 Free PMC article.
Tay-Sachs disease (TSD) is an inherited neurological disorder caused by deficiency of hexosaminidase A (HexA). ...Cerebrospinal fluid (CSF) HexA activity increased from baseline and remained stable in both patients. TSD-002 showed disease stabilization
Tay-Sachs disease (TSD) is an inherited neurological disorder caused by deficiency of hexosaminidase A (HexA). ...Cereb
Tay-Sachs disease-causing mutations and neutral polymorphisms in the Hex A gene.
Myerowitz R. Myerowitz R. Hum Mutat. 1997;9(3):195-208. doi: 10.1002/(SICI)1098-1004(1997)9:3<195::AID-HUMU1>3.0.CO;2-7. Hum Mutat. 1997. PMID: 9090523 Review.
Tay-Sachs disease is an autosomal recessive disorder affecting the central nervous system. ...Six nonsense mutations and 14 splice site lesions result from single base substitutions, and all but one of the splice site lesions cause a severe form of Tay
Tay-Sachs disease is an autosomal recessive disorder affecting the central nervous system. ...Six nonsense mutations an
Tay-Sachs disease.
Gelbart M. Gelbart M. Nurs Times. 1998 Mar 18-24;94(11):39. Nurs Times. 1998. PMID: 9697531 Review. No abstract available.
Genetics and Therapies for GM2 Gangliosidosis.
Cachon-Gonzalez MB, Zaccariotto E, Cox TM. Cachon-Gonzalez MB, et al. Curr Gene Ther. 2018;18(2):68-89. doi: 10.2174/1566523218666180404162622. Curr Gene Ther. 2018. PMID: 29618308 Free PMC article. Review.
Tay-Sachs disease, caused by impaired beta-N-acetylhexosaminidase activity, was the first GM2 gangliosidosis to be studied and one of the most severe and earliest lysosomal diseases to be described. ...Inherited as a classical autosomal recessive disorder, th
Tay-Sachs disease, caused by impaired beta-N-acetylhexosaminidase activity, was the first GM2 gangliosidosis to be stud
[Tay-Sachs disease].
Itoh T, Miura AB. Itoh T, et al. Ryoikibetsu Shokogun Shirizu. 1998;(22 Pt 3):389-92. Ryoikibetsu Shokogun Shirizu. 1998. PMID: 9851170 Review. Japanese. No abstract available.
Late-onset Tay-Sachs disease.
Barritt AW, Anderson SJ, Leigh PN, Ridha BH. Barritt AW, et al. Pract Neurol. 2017 Oct;17(5):396-399. doi: 10.1136/practneurol-2017-001665. Epub 2017 Jul 24. Pract Neurol. 2017. PMID: 28739864
(Gly269Ser)), confirming the very rare diagnosis of adult-onset Tay-Sachs disease....
(Gly269Ser)), confirming the very rare diagnosis of adult-onset Tay-Sachs disease....
[Tay-Sachs disease].
Tanaka A. Tanaka A. Nihon Rinsho. 1993 Sep;51(9):2281-5. Nihon Rinsho. 1993. PMID: 8411703 Review. Japanese.
In the severest phenotype of Tay-Sachs disease (infantile form), mRNA of beta-hexosaminidase alpha subunit is not produced or is unstable such as in French Canadian patients or in Jewish patients with infantile Tay-Sachs disease, or the p …
In the severest phenotype of Tay-Sachs disease (infantile form), mRNA of beta-hexosaminidase alpha subunit is not produ …
Cherry-red spot.
Suvarna JC, Hajela SA. Suvarna JC, et al. J Postgrad Med. 2008 Jan-Mar;54(1):54-7. doi: 10.4103/0022-3859.39196. J Postgrad Med. 2008. PMID: 18296811 No abstract available.
Prenatal Diagnosis of Tay-Sachs Disease.
Zhang J, Chen H, Kornreich R, Yu C. Zhang J, et al. Methods Mol Biol. 2019;1885:233-250. doi: 10.1007/978-1-4939-8889-1_16. Methods Mol Biol. 2019. PMID: 30506202
Tay-Sachs disease (TSD) is an autosomal recessive lysosomal storage disorder caused by mutations of the HEXA gene resulting in the deficiency of hexosaminidase A (Hex A) and subsequent neuronal accumulation of G(M2) gangliosides. Infantile TSD is a devastatin
Tay-Sachs disease (TSD) is an autosomal recessive lysosomal storage disorder caused by mutations of the HEXA gene resul
1,956 results